Sending your rat tails in. DNA testing for anticoagulant resistance

Sending your rat tails in. DNA testing for anticoagulant resistance

Recent break through in Germany led by Dr Hans-Joachim Pelz on the DNA sequencing of the resistant rats. 

The gene was given the name  VKORC1. It became possible for the first time to see how the DNA changes over time with the development of anticagulant resistance. 

In brief, different mutations in different places have evolved over time in the common Norway rat. Occasionally, the same mutation was found in rats from other countries. Meaning either the mutation happened at the same time or that the rat populations developed from the same stock. 

Dr Colin Prescott (University of Reading), a member of RRAG, and his co-workers who provide resistance monitoring and mapping information. To be able to say if the rodent is resistant or not, these tests require only the tip of the tail to be sent to Reading University. 

A link can be found here:

https://research.reading.ac.uk/resistant-rats/rat-resistance-testing/

 

Send in your rat tails

 


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